| 名稱 | TP53 p.R249G Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10158 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | TP53 p.R249G Reference Standard |
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10158TP53 p.R249G Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
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CBP10158 | |
| Format | Genomic DNA |
| Description | TP53 R249G is a hotspot mutation that lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). R249G results in decreased activation of Tp53 target genes, as well as increased proliferation and resistance to apoptosis in cell culture (PMID: 23246812). |
| Technical Data | |
| DNA Change: | c.745A>G |
| AA Change | p.R249G |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50% |
| Transcript | ENST00000269305 |
| Cosmic ID | COSM10668 |
| Chr position(GRCh37) | chr17:7577536 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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